Episode 332

Chronic Myeloid Leukemia — An Interview with Prof Andreas Hochhaus

Featuring an interview with Prof Andreas Hochhaus, including the following topics:

  • Biology of chronic myeloid leukemia (CML) and rationale for current therapeutic approaches; importance of cytogenetic testing (0:00)
  • Mechanistic differences among first-generation tyrosine kinase inhibitors (TKIs), second-generation TKIs and asciminib (6:09)
  • Potential mechanisms of adverse events documented with TKIs (10:23)
  • Recent survey of patients with CML regarding goals of therapy and clinical implications; considerations for discontinuation of therapy (16:23)
  • Comparative tolerability of asciminib and other agents used to manage CML; promoting adherence to treatment plans for patients (27:14)
  • Comparative efficacy of asciminib and other agents used to treat CML (40:01)
  • Potential areas for improvement in community oncology practice patterns; family planning in the context of CML treatment (43:53)
  • Practical care strategies for CML patients; future developments (52:32)

CME information and select publications

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Oncology Today with Dr Neil Love
A Research To Practice Podcast for Oncology Clinicians

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